Macrolide antibiotic agent obtained from cultures of a strain of Streptomyces erythraeus found in soil; active against Corynebacterium diphtheriae and several other species of Corynebacterium, Group A hemolytic streptococci, Streptococcus pneumoniae, Legionella, Mycoplasma pneumoniae, and Bordetella pertussis.
Side-effects Gastrointestinal intestinal disturbances such as diarrhea, nausea, abdominal pain and vomiting are fairly common so it tends not to be prescribed as a first-line drug.
Due to the high concentration in phagocytes, erythromycin is actively transported to the site of infection, where during active phagocytosis, large concentrations of erythromycin are released.
Oral erythromycin extends cardiac repolarization. Metabolism Most of erythromycin is metabolised by demethylation in the liver.
This binding process inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins.
Woodward and a large team of researchers reported the first stereocontrolled asymmetric chemical synthesis of Erythromycin A. Available forms Erythromycin is available in enteric-coated tablets, oral suspensions, opthalmic solutions, ointments, gels and injections. Cholestatic jaundice, Stevens-Johnson syndrome and toxic epidermal necrolysis are some other rare side effects that may occur.
Available as the estolate, ethylcarbonate, ethylsuccinate, gluceptate, lactobionate, stearate, and salts; active against Legionella and Mycoplasma pneumoniae. More serious side-effects, such as reversible deafness are rare.
Often used as a substitute antibiotic in penicillin-allergic patients. Erythromycin has been shown to increase the probability of pyloric stenosis in children whose mothers took the drug during the late stages of pregnancy or while nursing. Here are all the possible meanings and translations of the word Erythromycin.
Erythromycin is on the WHO official list. Pertaining to the ability to destroy or inhibit other living organisms. Erythromycin is very rapidly absorbed, and diffused into most tissues and phagocytes.
Allergic reactions, while uncommon, may occur, ranging from urticaria to anaphylaxis. History Abelardo Aguilar, a Filipino scientist, sent some soil samples to his employer Eli Lilly in It is metabolized by cytochrome P 3A isoenzymes and drugs such as nitroimidazole antifungals, verapamil, diltiazen and troleandomycin that inhibit CTP3A can increase the risk of ventricular arrhythmias and sudden death.
McGuire, managed to isolate Erythromycin from the metabolic products of a strain of Streptomyces erythreus found in the samples. In sensitive organisms, it inhibits protein synthesis by binding to 50S ribosomal subunits.
Link to this page: E-mycin, Ery-Tab et al. Available as the estolate, ethylcarbonate, ethylsuccinate, gluceptate, lactobionate, stearate, and salts; active against Legionella and M. It is effective against a wide variety of organisms, including gram-negative and gram-positive bacteria.
Cholestatic hepatitis, hypersensitivity reactions, and GI discomfort are other adverse effects associated with its use. The stearate can be given orally; the lactobionate is a soluble salt which can be administered intravenously. Hence, erythromycin should not be administered in patients using these drugs, or drugs that also prolong the QT time.Erythromycin is an antibiotic that possesses properties almost identical to those of penicillin.
It is classically used to treat patients who are allergic to penicillin, especially in cases of respiratory infection or chlamydia. Erythromycin is also. Erythromycin diffuses through the bacterial cell membrane and reversibly binds to the 50S subunit of the bacterial ribosome.
Costs & Medical Information. Advance Directives. Using Trusted Resources. Understanding Cancer The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with.
Definition of Erythromycin in the killarney10mile.com dictionary. Meaning of Erythromycin. What does Erythromycin mean? Information and translations of Erythromycin in the most comprehensive dictionary definitions resource on the web.
Erythromycin. Health and Medicine Reference Covering Thousands of Diseases and Prescription Drugs. Find information on thousands of medical conditions and prescription drugs.
Erythromycin. Erythromycin is a macrolide antibiotic which has an antimicrobial spectrum similar to or slightly wider than that of penicillin, and is often used for people.
Erythromycin is a prescription drug commonly used within the medical field, in place of penicillins, as a treatment option for infections caused by prokaryotic microorganisms or ‘bacteria’ (U.S. Department of Health and Human Services, ).
Definitions of Erythromycin for Medical & General Audiences. Erythromycin Defined Audience One: Medical Professional Erythromycin, a selectively prophylactic antibiotic, regularly utilized as a substitute for penicillins in the case of allergic reactions, is used.Download